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Article

Prenatal Lipopolysaccharide Exposure Promotes Dyslipidemia in the Male Offspring Rats

16 May 2018

Abstract excerpt

Inflammation is critical to the pathogenesis of cardiovascular diseases (CVDs). We have uncovered intrauterine inflammation induced by lipopolysaccharide (LPS) increases CVDs in adult offspring rats. The present study aimed to explore the role of prenatal exposure to LPS on the lipid profiles in male offspring rats and to further assess their susceptibility to high fat diet (HFD). Maternal LPS (0.79 mg/kg)...

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PMID: 29867579
DOI: 10.3389/fphys.2018.00542

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