Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Giant cell lesion of the jaw as a presenting feature of Noonan syndrome.

BMJ case reports - 30 May 2018

Sinnott Bridget P, Patel Maya

Abstract excerpt

This is a case of a 20-year-old woman who presented with a left jaw mass which was resected and found to be a giant cell granuloma of the mandible. Her history and physical examination were suggestive for Noonan syndrome which was confirmed with genetic testing and the finding of a PTPN11 gene mutation which has rarely been associated with giant cell lesions of the jaw. Given her particular genetic mutation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Treatment Outcome
Share to PTPN11 gene
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Noonan Syndrome

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 11

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29848529
DOI: 10.1136/bcr-2017-224115
PMCID: PMC5976125

Genes

PTPN11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Giant cell lesion of the jaw as a presenting feature of Noonan syndrome.PMID 29848529Read ↗

Multiple central giant cell lesions with a Noonan-like phenotype.Semantic proximity Read ↗

Multiple versus solitary giant cell lesions of the jaw: Similar or distinct entities?Semantic proximity Read ↗

Towards better understanding of giant cell granulomas of the oral cavity.Semantic proximity Read ↗

Phenotypic and genotypic characterisation of Noonan-like/multiple giant cell lesion syndrome.Semantic proximity Read ↗

Noonan syndrome with multiple Giant cell lesions, management and treatment with surgery and interferon alpha-2a therapy: Case report.Semantic proximity Read ↗

Noonan-like/multiple giant cell lesion syndrome in two adult patients with SOS1 gene mutations.Semantic proximity Read ↗

SOS1 and PTPN11 mutations in five cases of Noonan syndrome with multiple giant cell lesions.Semantic proximity Read ↗

Making sense of giant cell lesions of the jaws (GCLJ): lessons learned from next-generation sequencing.Semantic proximity Read ↗

Multiple giant cell lesions in a patient with Noonan syndrome with multiple lentigines.Semantic proximity Read ↗

Multiple giant cell lesions in patients with Noonan syndrome and cardio-facio-cutaneous syndrome.Semantic proximity Read ↗

Two cases of multiple ossifying fibromas in the jaws.Semantic proximity Read ↗

Analysis of giant cell tumour of bone cells for Noonan syndrome/cherubism-related mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.