Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single cell genomics to study DNA and chromosome changes in human gametes and embryos.

Methods in cell biology - 1 Jan 2018

Blanshard Robert C, Chen Chongyi, Xie Xiaoliang Sunney, Hoffmann Eva R

Abstract excerpt

Genomic and chromosomal changes occur with a high rate in the germline and preimplantation embryos. To study such changes directly in the germline of mammals requires access to material as well as single cell genomics. Recent improvements in embryology and single-cell DNA amplification make it possible to study the genomic changes directly in human oocytes, sperm, and preimplantation embryos. This is particularly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human
Share to DNA
Share to Embryo, Mammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Genomics

Share to Germ Cells

Share to Oocytes

Share to Single-Cell Analysis

Source

Identifiers

PMID: 29804682
DOI: 10.1016/bs.mcb.2018.03.037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single cell genomics to study DNA and chromosome changes in human gametes and embryos.PMID 29804682Read ↗

Genome analyses of single human oocytes.Semantic proximity Read ↗

Long-read-based single sperm genome sequencing for chromosome-wide haplotype phasing of both SNPs and SVs.Semantic proximity Read ↗

PCR analysis of DNA sequences in single cells: single sperm gene mapping and genetic disease diagnosis.Semantic proximity Read ↗

Long-read whole-genome sequencing-based concurrent haplotyping and aneuploidy profiling of single cellsSemantic proximity Read ↗

Clinical-grade whole genome sequencing-based haplarithmisis enables all forms of preimplantation genetic testingSemantic proximity Read ↗

Long-read whole-genome sequencing-based concurrent haplotyping and aneuploidy profiling of single cellsSemantic proximity Read ↗

Preimplantation genetic diagnosis guided by single-cell genomicsSemantic proximity Read ↗

Embryo genome profiling by single-cell sequencing for preimplantation genetic diagnosis in a β-thalassemia family.Semantic proximity Read ↗

Whole genome amplification from single cells in preimplantation genetic diagnosis and prenatal diagnosisSemantic proximity Read ↗

Whole genome amplification from a single cell: a new era for preimplantation genetic diagnosis.Semantic proximity Read ↗

Clinical-grade whole genome sequencing-based haplarithmisis enables all forms of preimplantation genetic testingSemantic proximity Read ↗

Preimplantation single-cell analysis of multiple genetic loci by whole-genome amplification.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.