Article
Association of Single-Nucleotide Polymorphisms in Age-Related Macular Degeneration With Pseudodrusen: Secondary Analysis of Data From the Comparison of AMD Treatments Trials.
JAMA ophthalmology - 1 Jun 2018
Lin Lisa Y, Zhou Qiang, Hagstrom Stephanie, Maguire Maureen G, Daniel Ebenezer, Grunwald Juan E, Martin Daniel F, Ying Gui-Shuang
Abstract excerpt
Importance: Previous studies investigating the association of single-nucleotide polymorphisms (SNPs) that confer increased risk of age-related macular degeneration (AMD) with pseudodrusen have yielded conflicting results and have not evaluated other AMD SNPs or pseudodrusen subtypes. Objective: To determine the association of SNPs in the complement factor H (CFH), age-related maculopathy susceptibility 2 (ARMS2),...
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