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40 YEARS OF IGF1: The emerging connections between IGF1, the intestinal microbiome, Lactobacillus strains and bone growth

22 May 2018

Abstract excerpt

In most animal species, postnatal growth is controlled by conserved insulin/insulin-like growth factor (IGF) signaling. In mammals, juvenile growth is characterized by a longitudinal bone growth resulting from the ossification of the growth plate. This ossification is under IGF1 influence through endocrine and paracrine mechanisms. Moreover, the nutritional status has been largely described as an important factor...

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PMID: 29789323
DOI: 10.1530/jme-17-0292

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