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Article

Recent evolution of the human skin barrier.

Experimental dermatology - 1 Aug 2018

Brettmann Erin A, de Guzman Strong Cristina

Abstract excerpt

The skin is the first line of defense against the environment, with the epidermis as the outermost tissue providing much of the barrier function. Given its direct exposure to and encounters with the environment, the epidermis must evolve to provide an optimal barrier for the survival of an organism. Recent advances in genomics have identified a number of genes for the human skin barrier that have undergone...

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Source

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Identifiers

PMID: 29787621
DOI: 10.1111/exd.13689
PMCID: PMC6392702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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