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Article

Clinical phenotypes and survival of pre-capillary pulmonary hypertension in systemic sclerosis.

PloS one - 1 Jan 2018

Launay David, Montani David, Hassoun Paul M, Cottin Vincent, Le Pavec Jérôme, Clerson Pierre, Sitbon Olivier, Jaïs Xavier, Savale Laurent, Weatherald Jason, Sobanski Vincent, Mathai Stephen C, Shafiq Majid, Cordier Jean-François, Hachulla Eric, Simonneau Gérald, Humbert Marc

Abstract excerpt

Pre-capillary pulmonary hypertension (PH) in systemic sclerosis (SSc) is a heterogeneous condition with an overall bad prognosis. The objective of this study was to identify and characterize homogeneous phenotypes by a cluster analysis in SSc patients with PH. Patients were identified from two prospective cohorts from the US and France. Clinical, pulmonary function, high-resolution chest tomography, hemodynamic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29763468
DOI: 10.1371/journal.pone.0197112
PMCID: PMC5953495

Genes

PAH

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