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Article

Genetic variants in dyf-7 validated by droplet digital PCR are not drivers for ivermectin resistance in Haemonchus contortus.

International journal for parasitology. Drugs and drug resistance - 1 Aug 2018

Elmahalawy Safaa T, Halvarsson Peter, Skarin Moa, Höglund Johan

Abstract excerpt

Resistance to ivermectin (IVM) in the nematode Haemonchus contortus in small ruminants is an increasing problem throughout the world. Access to molecular diagnostics will allow early detection of IVM resistance, which in turn can limit the spread of resistant isolates. One candidate gene which has recently been suggested as a marker for IVM resistance is that for dye-filling protein (dyf-7). In this study, we...

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Anthelmintics
Haemonchiasis
Haemonchus
Ivermectin
Multidrug Resistance-Associated Proteins

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PMID: 29758488
DOI: 10.1016/j.ijpddr.2018.04.005
PMCID: PMC6019680

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