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Article

Anti-IL17 treatment ameliorates Down syndrome phenotypes in mice.

Brain, behavior, and immunity - 1 Oct 2018

Rueda Noemí, Vidal Verónica, García-Cerro Susana, Narcís Josep Oriol, Llorens-Martín María, Corrales Andrea, Lantigua Sara, Iglesias Marcos, Merino Jesús, Merino Ramón, Martínez-Cué Carmen

Abstract excerpt

Down syndrome (DS) is characterized by structural and functional anomalies that are present prenatally and that lead to intellectual disabilities. Later in life, the cognitive abilities of DS individuals progressively deteriorate due to the development of Alzheimer's disease (AD)-associated neuropathology (i.e., β-amyloid (Aβ) plaques, neurofibrillary tangles (NFTs), neurodegeneration, synaptic pathology,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29758264
DOI: 10.1016/j.bbi.2018.05.008

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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