Article
Pathophysiology and Genetics of Bronchiectasis Unrelated to Cystic Fibrosis.
Lung - 1 Aug 2018
Nikolic Aleksandra
Abstract excerpt
Bronchiectasis is characterized by deregulated inflammatory response and recurrent bacterial infection resulting in progressive lung damage and an irreversible dilatation of bronchi and bronchioles. Generally accepted model of the development of bronchiectasis is the "vicious cycle hypothesis" that proposes compromising of the mucociliary clearance by an initial event, which leads to the infection of the...
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