Article
FAST: Rapid determinations of antibiotic susceptibility phenotypes using label-free cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 Jun 2018
Huang Tzu-Hsueh, Tzeng Yih-Ling, Dickson Robert M
Abstract excerpt
Sepsis, a life-threatening immune response to blood infections (bacteremia), has a ∼30% mortality rate and is the 10th leading cause of US hospital deaths. The typical bacterial loads in adult septic patients are ≤100 bacterial cells (colony forming units, CFU) per ml blood, while pediatric patients exhibit only ∼1000 CFU/ml. Due to the low numbers, bacteria must be propagated through ∼24-hours blood cultures to...
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