Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic young adults.

doi:10.1371/journal.pntd.0006377

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Article

Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic young adults.

PLoS neglected tropical diseases - 1 Apr 2018

Komas Narcisse Patrice, Ghosh Sumantra, Abdou-Chekaraou Mariama, Pradat Pierre, Al Hawajri Nasser, Manirakiza Alexandre, Laghoe Gina Laure, Bekondi Claudine, Brichler Ségolène, Ouavéné Jean-Omer, Sépou Abdoulaye, Yambiyo Brice Martial, Gody Jean Chrysostome, Fikouma Valentin, Gerber Athénais, Abeywickrama Samarakoon Natali, Alfaiate Dulce, Scholtès Caroline, Martel Nora, Le Gal Frédéric, Lo Pinto Hugo, Amri Ikram, Hantz Olivier, Durantel David, Lesbordes Jean-Louis, Gordien Emmanuel, Merle Philippe, Drugan Tudor, Trépo Christian, Zoulim Fabien, Cortay Jean-Claude, Kay Alan Campbell, Dény Paul

Abstract excerpt

Hepatitis delta virus (HDV) increases morbidity in Hepatitis B virus (HBV)-infected patients. In the mid-eighties, an outbreak of HDV fulminant hepatitis (FH) in the Central African Republic (CAR) killed 88% of patients hospitalized in Bangui. We evaluated infections with HBV and HDV among students and pregnant women, 25 years after the fulminant hepatitis (FH) outbreak to determine (i) the prevalence of HBV and...

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PMID: 29698488
DOI: 10.1371/journal.pntd.0006377
PMCID: PMC5940242

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