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Article

Bevacizumab Reduces S100A9-Positive MDSCs Linked to Intracranial Control in Patients with EGFR-Mutant Lung Adenocarcinoma.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2018

Feng Po-Hao, Chen Kuan-Yuan, Huang Yu-Chen, Luo Ching-Shan, Wu Shen Ming, Chen Tzu-Tao, Lee Chun-Nin, Yeh Chi-Tai, Chuang Hsiao-Chi, Han Chia-Li, Lin Chiou-Feng, Lee Wei-Hwa, Kuo Chih-Hsi, Lee Kang-Yun

Abstract excerpt

INTRODUCTION: In vitro models have demonstrated immune-modulating effects of bevacizumab (BEV). Combinations of an EGFR tyrosine kinase inhibitor (TKI) with BEV improve progression-free survival (PFS) in patients with EGFR-mutated lung adenocarcinoma. How BEV confers this clinical effect and the underlying mechanisms of its effect are not clear. METHODS: A total of 55 patients with stage 4 EGFR-mutated lung...

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Identifiers

PMID: 29684573
DOI: 10.1016/j.jtho.2018.03.032

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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