Article
Risk factors of brain metastasis during the course of EGFR-TKIs therapy for patients with EGFR-mutated advanced lung adenocarcinoma.
Oncotarget - 6 Dec 2016
Ma Xiaoyan, Zhu Hui, Guo Hongbo, Han Anqin, Wang Haiyong, Jing Wang, Zhang Yan, Kong Li, Yu Jinming
Abstract excerpt
Controversial value of prophylactic cranial irradiation (PCI) in NSCLC in terms of survival benefit prompted us to explore the possible risk factors for brain metastasis (BM) during the course of EGFR-TKIs therapy from EGFR-mutated advanced lung adenocarcinoma and identify the potential population most likely to benefit from PCI, because BM remains a therapeutically challenging issue. We retrospectively reviewed...
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