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Article

Viral proteins as a potential driver of histone depletion in dinoflagellates.

Nature communications - 18 Apr 2018

Irwin Nicholas A T, Martin Benjamin J E, Young Barry P, Browne Martin J G, Flaus Andrew, Loewen Christopher J R, Keeling Patrick J, Howe LeAnn J

Abstract excerpt

Within canonical eukaryotic nuclei, DNA is packaged with highly conserved histone proteins into nucleosomes, which facilitate DNA condensation and contribute to genomic regulation. Yet the dinoflagellates, a group of unicellular algae, are a striking exception to this otherwise universal feature as they have largely abandoned histones and acquired apparently viral-derived substitutes termed DVNPs...

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Identifiers

PMID: 29670105
DOI: 10.1038/s41467-018-03993-4
PMCID: PMC5906630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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