Article
Whole-genome sequences of 89 Chinese sheep suggest role of RXFP2 in the development of unique horn phenotype as response to semi-feralization.
GigaScience - 1 Apr 2018
Pan Zhangyuan, Li Shengdi, Liu Qiuyue, Wang Zhen, Zhou Zhengkui, Di Ran, Miao Benpeng, Hu Wenping, Wang Xiangyu, Hu Xiaoxiang, Xu Ze, Wei Dongkai, He Xiaoyun, Yuan Liyun, Guo Xiaofei, Liang Benmeng, Wang Ruichao, Li Xiaoyu, Cao Xiaohan, Dong Xinlong, Xia Qing, Shi Hongcai, Hao Geng, Yang Jean, Luosang Cuicheng, Zhao Yiqiang, Jin Mei, Zhang Yingjie, Lv Shenjin, Li Fukuan, Ding Guohui, Chu Mingxing, Li Yixue
Abstract excerpt
Background: Animal domestication has been extensively studied, but the process of feralization remains poorly understood. Results: Here, we performed whole-genome sequencing of 99 sheep and identified a primary genetic divergence between 2 heterogeneous populations in the Tibetan Plateau, including 1 semi-feral lineage. Selective sweep and candidate gene analysis revealed local adaptations of these sheep...
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