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Third trimester phthalate exposure is associated with DNA methylation of growth-related genes in human placenta

22 Sept 2016

Abstract excerpt

Strong evidence implicates maternal phthalate exposure during pregnancy in contributing to adverse birth outcomes. Recent research suggests these effects might be mediated through the improper regulation of DNA methylation in offspring tissue. In this study, we examined associations between prenatal phthalate exposure and DNA methylation in human placenta. We recruited 181 mother-newborn pairs (80 fetal growth...

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PMID: 27653773
DOI: 10.1038/srep33449

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