Article
Intrastrain heterogeneity of the mgpB gene in Mycoplasma genitalium is extensive in vitro and in vivo and suggests that variation is generated via recombination with repetitive chromosomal sequences.
Infection and immunity - 1 Jul 2006
Iverson-Cabral Stefanie L, Astete Sabina G, Cohen Craig R, Rocha Eduardo P C, Totten Patricia A
Abstract excerpt
Mycoplasma genitalium is associated with reproductive tract disease in women and may persist in the lower genital tract for months, potentially increasing the risk of upper tract infection and transmission to uninfected partners. Despite its exceptionally small genome (580 kb), approximately 4% is composed of repeated elements known as MgPar sequences (MgPa repeats) based on their homology to the mgpB gene that...
Read the complete abstract on PubMedTopics
- Adhesins, Bacterial
- Adult
- Bacterial Adhesion
- Base Sequence
- Chromosomes, Bacterial