Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Crosstalk between gut microbiota and Sirtuin-3 in colonic inflammation and tumorigenesis

1 Apr 2018

Abstract excerpt

Colorectal cancer (CRC) is a disease involving a variety of genetic and environmental factors. Sirtuin-3 (Sirt3) is expressed at a low level in cancer tissues of CRC, but it is unclear how Sirt3 modulates colonic tumorigenesis. In this study, we found that gut microbiota play a central role in the resistance to CRC tumor formation in wild-type (WT) mice through APC (Adenomatous Polyposis Coli)-mutant mouse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Gut microbiota and health
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29650970
DOI: 10.1038/s12276-017-0002-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Crosstalk between gut microbiota and Sirtuin-3 in colonic inflammation and tumorigenesisPMID 29650970Read ↗

Probiotics modify human intestinal mucosa-associated microbiota in patients with colorectal cancerSemantic proximity Read ↗

Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal MicrobiotaSemantic proximity Read ↗

Naringenin Inhibits Colorectal Cancer associated with a High-Fat Diet through Modulation of Gut Microbiota and IL-6/STAT3 PathwaySemantic proximity Read ↗

Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice.Semantic proximity Read ↗

Deficiency of miRNA-149-3p shaped gut microbiota and enhanced dextran sulfate sodium-induced colitisSemantic proximity Read ↗

Current Hypothesis for the Relationship between Dietary Rice Bran Intake, the Intestinal Microbiota and Colorectal Cancer PreventionSemantic proximity Read ↗

Human Gut Microbiota and Gastrointestinal CancerSemantic proximity Read ↗

Interaction between microbiota and immunity and its implication in colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.