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Article

Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways.

Experimental & molecular medicine - 13 Apr 2018

Liu Gen-Xia, Ma Shu, Li Yao, Yu Yan, Zhou Yi-Xiang, Lu Ya-Die, Jin Lin, Wang Zi-Lu, Yu Jin-Hua

Abstract excerpt

The putative tumor suppressor microRNA let-7c is extensively associated with the biological properties of cancer cells. However, the potential involvement of let-7c in the differentiation of mesenchymal stem cells has not been fully explored. In this study, we investigated the influence of hsa-let-7c (let-7c) on the proliferation and differentiation of human dental pulp-derived mesenchymal stem cells (DPMSCs)...

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Identifiers

PMID: 29650947
DOI: 10.1038/s12276-018-0048-7
PMCID: PMC5938007

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CCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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