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Does human endometrial LGR5 gene expression suggest the existence of another hormonally regulated epithelial stem cell niche?

27 Mar 2018

Abstract excerpt

STUDY QUESTION: Is human endometrial leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) gene expression limited to the postulated epithelial stem cell niche, stratum basalis glands, and is it hormonally regulated? SUMMARY ANSWER: LGR5 expressing cells are not limited to the postulated stem cell niche but LGR5 expression is hormonally regulated. WHAT IS KNOWN ALREADY: The human endometrium is a...

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PMID: 29648645
DOI: 10.1093/humrep/dey083

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