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Genetic aberrations of the K-ras proto-oncogene in bladder cancer in relation to pesticide exposure.

Environmental science and pollution research international - 1 Aug 2018

Hameed Diaa A, Yassa Heba A, Agban Michael N, Hanna Randa T, Elderwy Ahmed M, Zwaita Mohamed A

Abstract excerpt

In Egypt, bladder cancer is one of the most popular cancers, accounting for 31% of all cancer cases. It ranks first in males about 16.2% of male cancer. The incidence in rural areas among males is near 32 per 100,000. The exact etiology of bladder cancer is still unknown; K-ras gene is known as a critical DNA target for chemical carcinogens such as pesticide. Some occupational hazard exposure is thought to be...

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PMID: 29644616
DOI: 10.1007/s11356-018-1840-6

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