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Article

A genetic variant in the promoter of lncRNA MALAT1 is related to susceptibility of ischemic stroke.

Lipids in health and disease - 1 Apr 2020

Wang Yan, Gu Xi-Xi, Huang Hua-Tuo, Liu Chun-Hong, Wei Ye-Sheng

Abstract excerpt

BACKGROUND: Metastasis-associated lung adenocarcinoma transcript-1 (MALAT1) was aberrantly expressed in diverse diseases. Particularly in ischemic stroke (IS), the abnormal expression of MALAT1 played important roles including promotion of angiogenesis, inhibition of apoptosis and inflammation and regulation of autophagy. However, the effects of genetic variation (single nucleotide polymorphisms, SNPs) of MALAT1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32238151
DOI: 10.1186/s12944-020-01236-4
PMCID: PMC7110643

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