Article
The MALAT1 gene polymorphism and its relationship with the onset of congenital heart disease in Chinese.
Bioscience reports - 29 May 2018
Li Qian, Zhu Wenying, Zhang Bei, Wu Yiping, Yan Sen, Yuan Yufeng, Zhang Haiyan, Li Jie, Sun Kai, Wang Hua, Yu Tingting
Abstract excerpt
Many long non-coding RNAs (lncRNAs), including lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), are involved in various cardiac diseases. We evaluated the effects of tag single nucleotide polymorphisms (tag-SNPs) on MALAT1 gene in a Chinese population of children with congenital heart disease (CHD). In the present study, 713 CHD patients and 730 gender- and age-matched children without CHD...
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