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Article

A novel single nucleotide polymorphism in exon 3 of MYOC enhances the risk of glaucoma.

PloS one - 1 Jan 2018

Nazir Sabeen, Mukhtar Maryam, Shahnawaz Maryam, Farooqi Shaima, Fatima Naz, Mehmood Rabia, Sheikh Nadeem

Abstract excerpt

Genetic polymorphismsof MYOCalter the myocilin protein,which leads to disruption of thenormal regulation of intraocular pressure (IOP) that ultimately causes glaucoma.Theaim of the present study was to identify the polymorphism in exon 3 of the MYOC gene of theglaucoma patients in Lahore, Pakistan. We conducted a case-control study with 100 patients and 100 controls subjects. We extracted DNA from blood...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29630620
DOI: 10.1371/journal.pone.0195157
PMCID: PMC5890997

Genes

MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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A novel single nucleotide polymorphism in exon 3 of MYOC enhances the risk of glaucoma.PMID 29630620Read ↗

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