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Article

Association of the MYOC p.(Gln368Ter) Variant With Glaucoma in a Finnish Population.

JAMA ophthalmology - 1 Jul 2021

Liuska Perttu J, Lemmelä Susanna, Havulinna Aki S, Kaarniranta Kai, Uusitalo Hannu, Laivuori Hannele, Kiiskinen Tuomo, Daly Mark J, Palotie Aarno, Turunen Joni A

Abstract excerpt

IMPORTANCE: The c.1102C>T, p.(Gln368Ter) variant in the myocilin (MYOC) gene is a known risk allele for glaucoma. It is the most common MYOC risk variant for glaucoma among individuals of European ancestry, and its prevalence is highest in Finland. Furthermore, exfoliation syndrome has high prevalence in Scandinavia, making the Finnish population ideal to study the association of the variant with different types...

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Identifiers

PMID: 34081096
DOI: 10.1001/jamaophthalmol.2021.1610
PMCID: PMC8176385

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