Article
Cannabidiol regulates behavioural alterations and gene expression changes induced by spontaneous cannabinoid withdrawal
6 Apr 2018
Abstract excerpt
Background and Purpose Cannabidiol (CBD) represents a promising therapeutic tool for treating cannabis use disorder (CUD). This study aimed to evaluate the effects of CBD on the behavioural and gene expression alterations induced by spontaneous cannabinoid withdrawal. Experimental Approach Spontaneous cannabinoid withdrawal was evaluated 12 h after cessation of CP‐55,940 treatment (0.5 mg·kg−1every 12 h, i.p.; 7...
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