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High frequency of M. leprae DNA detection in asymptomatic household contacts

2 Apr 2018

Abstract excerpt

BACKGROUND: Characterization of the Mycobacterium leprae genome has made possible the development of Polymerase Chain Reaction (PCR) systems that can amplify different genomic regions. Increased reliability and technical efficiency of quantitative PCR (qPCR) makes it a promising tool for early diagnosis of leprosy. Index cases that are multibacillary spread the bacillus silently, even before they are clinically...

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PMID: 29609530
DOI: 10.1186/s12879-018-3056-2

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