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Article

Associations of monoamine oxidase A gene first exon methylation with sexual abuse and current depression in women.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jul 2018

Checknita David, Ekström Tomas J, Comasco Erika, Nilsson Kent W, Tiihonen Jari, Hodgins Sheilagh

Abstract excerpt

Childhood physical abuse (PA) and sexual abuse (SA) interact with monoamine oxidase A (MAOA) gene polymorphism to modify risk for mental disorders. In addition, PA and SA may alter gene activity through epigenetic mechanisms such as DNA methylation, thereby further modifying risk for disorders. We investigated whether methylation in a region spanning the MAOA first exon and part of the first intron was associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29600412
DOI: 10.1007/s00702-018-1875-3
PMCID: PMC5999185

Genes

MAOA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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