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Article

The emerging clinical relevance of genomics in cancer medicine.

Nature reviews. Clinical oncology - 1 Jun 2018

Berger Michael F, Mardis Elaine R

Abstract excerpt

The combination of next-generation sequencing and advanced computational data analysis approaches has revolutionized our understanding of the genomic underpinnings of cancer development and progression. The coincident development of targeted small molecule and antibody-based therapies that target a cancer's genomic dependencies has fuelled the transition of genomic assays into clinical use in patients with...

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Identifiers

PMID: 29599476
DOI: 10.1038/s41571-018-0002-6
PMCID: PMC6658089

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