Article
Gene Expression Classifier vs Targeted Next-Generation Sequencing in the Management of Indeterminate Thyroid Nodules.
The Journal of clinical endocrinology and metabolism - 1 Jun 2018
Livhits Masha J, Kuo Eric J, Leung Angela M, Rao Jianyu, Levin Mary, Douek Michael L, Beckett Katrina R, Zanocco Kyle A, Cheung Dianne S, Gofnung Yaroslav A, Smooke-Praw Stephanie, Yeh Michael W
Abstract excerpt
Context: Molecular testing has reduced the need for diagnostic hemithyroidectomy for indeterminate thyroid nodules. No studies have directly compared molecular testing techniques. Objective: Compare the diagnostic performance of Afirma Gene Expression Classifier (GEC) with that of ThyroSeq v2 next-generation sequencing assay. Design: Parallel randomized trial, monthly block randomization of patients with Bethesda...
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