Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zebrafish: A Pharmacogenetic Model for Anesthesia.

Methods in enzymology - 1 Jan 2018

Bedell Victoria, Buglo Elena, Marcato Daniel, Pylatiuk Christian, Mikut Ralf, Stegmaier Johannes, Scudder Will, Wray Maxwell, Züchner Stephan, Strähle Uwe, Peravali Ravindra, Dallman Julia E

Abstract excerpt

General anesthetics are small molecules that interact with and effect the function of many different proteins to promote loss of consciousness, amnesia, and sometimes, analgesia. Owing to the complexity of this state transition and the transient nature of these drug/protein interactions, anesthetics can be difficult to study. The zebrafish is an emerging model for the discovery of both new genes required for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia
Share to Anesthetics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Biotransformation

Share to Drug Discovery

Share to Gene Editing

Share to High-Throughput Screening Assays

Share to Pharmacogenomic Variants

Share to Propofol

Source

Open in PubMed Open full text

Identifiers

PMID: 29588029
DOI: 10.1016/bs.mie.2018.02.004
PMCID: PMC10559369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zebrafish: A Pharmacogenetic Model for Anesthesia.PMID 29588029Read ↗

Studies on target genes of general anesthetics.Semantic proximity Read ↗

Zebrafish As a Genetic Model in Pre-Clinical Drug Testing and ScreeningSemantic proximity Read ↗

Advancing epilepsy treatment through personalized genetic zebrafish models.Semantic proximity Read ↗

Zebrafish Larvae Behavior Models as a Tool for Drug Screenings and Pre-Clinical Trials: A Review.Semantic proximity Read ↗

The zebrafish as a model system for assessing the reinforcing properties of drugs of abuse.Semantic proximity Read ↗

Simple vertebrate models for chemical genetics and drug discovery screens: lessons from zebrafish and Xenopus.Semantic proximity Read ↗

The Use of the Zebrafish Model to Aid in Drug Discovery and Target ValidationSemantic proximity Read ↗

Characterization and Phenotypic Assessment of Zebrafish Disease Models for Splice Modulation Studies.Semantic proximity Read ↗

Zebrafish as a developmental model organism for pediatric research.Semantic proximity Read ↗

Zebrafish as an Innovative Tool for Epilepsy Modeling: State of the Art and Potential Future DirectionsSemantic proximity Read ↗

The genetics of response to volatile anesthetics in Caenorhabditis elegans.Semantic proximity Read ↗

Building a zebrafish toolkit for investigating the pathobiology of epilepsy and identifying new treatments for epileptic seizures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.