miR-143-3p regulates cell proliferation and apoptosis by targeting IGF1R and IGFBP5 and regulating the Ras/p38 MAPK signaling pathway in rheumatoid arthritis

Abstract excerpt

It has been demonstrated that the deregulation of microRNAs (miRNAs) affects the development of rheumatoid arthritis (RA). The primary objective of the current study was to determine the role of miR‑143‑3p in the progression of RA. The expression of miR‑143‑3p in synovium taken from patients with RA was assessed by reverse transcription‑quantitative polymerase chain reaction. The expression of miR‑143‑3p was...

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