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Article

Exacerbation induces a microbiota shift in sputa of COPD patients

26 Mar 2018

Abstract excerpt

Little is known about the microbiota shift induced by exacerbation in chronic obstructive pulmonary disease (COPD) patients. The sputa microbiota of COPD patients was evaluated when clinically stable and during acute exacerbations of the disease. Sputa microbiota was analyzed using 16S ribosomal RNA gene pyrosequencing and quantitative polymerase chain reaction-based pathogen detection. Nine COPD patients were...

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PMID: 29579057
DOI: 10.1371/journal.pone.0194355

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