Article
CK-2 of rainbow trout (Oncorhynchus mykiss) has two differentially regulated alleles that encode a functional chemokine.
Veterinary immunology and immunopathology - 1 Apr 2018
Semple Shawna L, Eshaque Shathi, Fujiki Kazuhiro, Tang Cynthia, Mitchell Leslie, Bols Niels C, Dixon Brian
Abstract excerpt
Rainbow trout chemokine 2 (CK-2) is currently the only known CC chemokine to have a mucin stalk. Further analysis of the mucin stalk region revealed a second, related CC chemokine sequence, denoted here as CK-2.1. This second sequence was determined to be an allele of CK-2 following genomic PCR analysis on several outbred individuals. Furthermore, in both in vivo and in vitro trials, CK-2 and CK-2.1 were both...
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