Article
Bounding measures of genetic similarity and diversity using majorization.
Journal of mathematical biology - 1 Sept 2018
Aw Alan J, Rosenberg Noah A
Abstract excerpt
The homozygosity and the frequency of the most frequent allele at a polymorphic genetic locus have a close mathematical relationship, so that each quantity places a tight constraint on the other. We use the theory of majorization to provide a simplified derivation of the bounds on homozygosity J in terms of the frequency M of the most frequent allele. The method not only enables simpler derivations of known...
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