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Article

Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans.

Scientific reports - 16 Mar 2018

Verboven K, Wouters K, Gaens K, Hansen D, Bijnen M, Wetzels S, Stehouwer C D, Goossens G H, Schalkwijk C G, Blaak E E, Jocken J W

Abstract excerpt

Obesity is associated with a disturbed adipose tissue (AT) function characterized by adipocyte hypertrophy, an impaired lipolysis and pro-inflammatory phenotype, which contributes to insulin resistance (IR). We investigated whether AT phenotype in different AT depots of obese individuals with and without type 2 diabetes mellitus (T2DM) is associated with whole-body IR. Subcutaneous (SC) and visceral (V) AT...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29549282
DOI: 10.1038/s41598-018-22962-x
PMCID: PMC5856747

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