Article
Clinical impact of minocycline on afatinib-related rash in patients with non-small cell lung cancer harboring epidermal growth factor receptor mutations.
Respiratory investigation - 1 Mar 2018
Goto Ayano, Ozawa Yuichi, Koda Keigo, Akahori Daisuke, Koyauchi Takashi, Amano Yusuke, Kakutani Takuya, Sato Yoshiko, Hasegawa Hirotsugu, Matsui Takashi, Yokomura Koshi, Suda Takafumi
Abstract excerpt
BACKGROUND: The management of skin toxicity is crucial for efficient afatinib treatment, but the role of tetracycline class antibiotics (TCs) in managing these rashes is relatively unknown. METHODS: We reviewed the clinical records of patients who were administered afatinib for the treatment of non-small cell lung cancer harboring epidermal growth factor receptor mutations between October 2014 and November 2016....
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