Article
Cost-effectiveness of KRAS, EGFR and ALK testing for decision making in advanced nonsmall cell lung carcinoma: the French IFCT-PREDICT.amm study.
The European respiratory journal - 1 Mar 2018
Loubière Sandrine, Drezet Alexandre, Beau-Faller Michèle, Moro-Sibilot Denis, Friard Sylvie, Wislez Marie, Blons Hélène, Daniel Catherine, Westeel Virginie, Madroszyk Anne, Léna Hervé, Merle Patrick, Mazières Julien, Zalcman Gérard, Lacave Roger, Antoine Martine, Morin Franck, Missy Pascale, Barlesi Fabrice, Auquier Pascal, Cadranel Jacques
Abstract excerpt
ALK rearrangement and EGFR/KRAS mutations constitute the primary biomarkers tested to provide targeted or nontargeted therapies in advanced nonsmall cell lung cancer (NSCLC) patients. Our objective was to assess the cost-effectiveness of biomarker testing for NSCLC.Between 2013 and 2014, 843 treatment-naive patients were prospectively recruited at 19 French hospitals into a longitudinal observational cohort...
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