Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

From somatic variants towards precision oncology: Evidence-driven reporting of treatment options in molecular tumor boards.

Genome medicine - 15 Mar 2018

Perera-Bel Júlia, Hutter Barbara, Heining Christoph, Bleckmann Annalen, Fröhlich Martina, Fröhling Stefan, Glimm Hanno, Brors Benedikt, Beißbarth Tim

Abstract excerpt

BACKGROUND: A comprehensive understanding of cancer has been furthered with technological improvements and decreasing costs of next-generation sequencing (NGS). However, the complexity of interpreting genomic data is hindering the implementation of high-throughput technologies in the clinical context: increasing evidence on gene-drug interactions complicates the task of assigning clinical significance to genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Genome, Human

Share to Genomics

Share to Medical Oncology

Share to Neoplasms

Share to Precision Medicine

Source

Open in PubMed Open full text

Identifiers

PMID: 29544535
DOI: 10.1186/s13073-018-0529-2
PMCID: PMC5856211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

From somatic variants towards precision oncology: Evidence-driven reporting of treatment options in molecular tumor boards.PMID 29544535Read ↗

Utility of public knowledge bases for the interpretation of comprehensive tumor molecular profiling results.Semantic proximity Read ↗

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer.Semantic proximity Read ↗

Clinical Use of Precision Oncology Decision SupportSemantic proximity Read ↗

Resources for Interpreting Variants in Precision Genomic Oncology ApplicationsSemantic proximity Read ↗

Optimized precision oncology through implementation of a comprehensive molecular analysis pipeline - relevance for additional therapeutic options.Semantic proximity Read ↗

A harmonized meta-knowledgebase of clinical interpretations of cancer genomic variantsSemantic proximity Read ↗

A Platform for Oncogenomic Reporting and InterpretationSemantic proximity Read ↗

The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretationsSemantic proximity Read ↗

Assessing actionability and incidental findings of germline variants in two precision oncology trials.Semantic proximity Read ↗

The Precision Medicine Knowledge Base: an online application for collaborative editing, maintenance and sharing of structured clinical-grade cancer mutations interpretationsSemantic proximity Read ↗

The Role of Next-Generation Sequencing in Precision Medicine: A Review of Outcomes in OncologySemantic proximity Read ↗

The Role of Next-Generation Sequencing in Precision Medicine: A Review of Outcomes in OncologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.