Article
Prevalence of Pathogenic Gene Mutations and Prognosis Do Not Differ in Isolated Left Ventricular Dysfunction Compared With Dilated Cardiomyopathy.
Circulation. Heart failure - 1 Mar 2018
Hazebroek Mark R, Krapels Ingrid, Verdonschot Job, van den Wijngaard Arthur, Vanhoutte Els, Hoos Marije, Snijders Luc, van Montfort Lieke, Witjens Maryvonne, Dennert Robert, Crijns Harry J G M, Brunner-La Rocca Hans-Peter, Brunner Han G, Heymans Stephane
Abstract excerpt
BACKGROUND: Genetic evaluation is recommended in patients with unexplained dilated cardiomyopathy (DCM), but its diagnostic yield and prognostic relevance in unexplained isolated left ventricular dysfunction (LVdys) is unknown. METHODS AND RESULTS: A total of 127 LVdys and 262 DCM patients underwent genetic screening. Long-term outcome consisted of a combined end point of life-threatening arrhythmia, heart...
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