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Article

Mainstreamed genetic testing for women with ovarian cancer: first-year experience.

Journal of medical genetics - 1 Mar 2019

Rahman Belinda, Lanceley Anne, Kristeleit Rebecca S, Ledermann Jonathan A, Lockley Michelle, McCormack Mary, Mould Tim, Side Lucy

Abstract excerpt

BACKGROUND: Ovarian cancer is the fifth most common cause of cancer death for women in the UK. Up to 18% of cases can be attributed to germline mutations in BRCA1 and BRCA2genes. Identifying patients who carry a BRCA mutation provides important information about potential response to treatment and eligibility for therapies such as poly ADP ribose polymerase (PARP) inhibitors. Implementation of systematic genetic...

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Identifiers

PMID: 29535157
DOI: 10.1136/jmedgenet-2017-105140

Genes

BRCA1
BRCA2

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