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Article

Turning on virulence: Mechanisms that underpin the morphologic transition and pathogenicity of Blastomyces

13 Mar 2018

Abstract excerpt

This review article focuses on the mechanisms underlying temperature adaptation and virulence of the etiologic agents of blastomycosis, Blastomyces dermatitidis, Blastomyces gilchristii, and Blastomyces percursus. In response to temperature, Blastomyces undergoes a reversible morphologic switch between hyphae and yeast known as the phase transition. The conversion to yeast for Blastomyces and related thermally...

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Identifiers

PMID: 29532714
DOI: 10.1080/21505594.2018.1449506

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