Article
An innovative mesothelioma treatment based on miR-16 mimic loaded EGFR targeted minicells (TargomiRs)
1 Feb 2018
Abstract excerpt
On September 2017, The Lancet Oncology published the safety and activity data of a first-in-human study of microRNA-loaded minicells as a treatment for recurrent malignant pleural mesothelioma patients by van Zandwijk and colleagues (1). The rationale of this interesting study relies on the potential inhibition of tumor growth through the restoration of miR-16 with a miRNA mimic that is delivered into the tumor...
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