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Article

Melanocyte abnormalities and senescence in the pathogenesis of idiopathic guttate hypomelanosis

8 Mar 2018

Abstract excerpt

BACKGROUND: Idiopathic guttate hypomelanosis (IGH) is a pigmentary disorder of unknown pathogenesis characterized by small discrete white macules. In the skin, epidermal melanin unit between melanocytes and keratinocytes is responsible for melanin synthesis and equal distribution of melanin pigment. OBJECTIVE: Therefore, this study was designed to check the role of melanocytes in the pathogenesis of IGH. METHODS:...

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Share to Cutaneous Melanoma Detection and Management
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Identifiers

PMID: 29516488
DOI: 10.1111/ijd.13960

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