Article
Significant Association between OPG/TNFRSF11B Variant and Common Complex Ischemic Stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jun 2018
Xiong Xin, Naji Duraid Hamied, Wang Binbin, Zhao Yuanyuan, Wang Junhan, Wang Dan, Zhang Yuting, Li Sisi, Chen Shanshan, Huang Yufeng, Yang Qin, Wang Xiaojing, Yin Dan, Tu Xin, Chen Qiuyun, Ma Xu, Xu Chengqi, Wang Qing K
Abstract excerpt
BACKGROUND: The serum level of osteoprotegerin (encoded by OPG or TNFRSF11B) was previously shown to be increased in patients with ischemic stroke. A single nucleotide polymorphism rs3134069 in the TNFRSF11B gene was previously associated with ischemic stroke in a population of diabetic patients in Italy. It remains to be determined whether rs3134069 is associated with ischemic stroke in the general population or...
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