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Article

Common variants of ARID1A and KAT2B are associated with obesity in Indian adolescents.

Scientific reports - 2 Mar 2018

Giri Anil K, Parekatt Vaisak, Dwivedi Om Prakash, Banerjee Priyanka, Bandesh Khushdeep, Prasad Gauri, Tandon Nikhil, Bharadwaj Dwaipayan

Abstract excerpt

Obesity involves alterations in transcriptional programs that can change in response to genetic and environmental signals through chromatin modifications. Since chromatin modifications involve different biochemical, neurological and molecular signaling pathways related to energy homeostasis, we hypothesize that genetic variations in chromatin modifier genes can predispose to obesity. Here, we assessed the...

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Identifiers

PMID: 29500370
DOI: 10.1038/s41598-018-22231-x
PMCID: PMC5834613

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