Modulatory effects of trophoblast-secreted CXCL12 on the migration and invasion of human first-trimester decidual epithelial cells are mediated by CXCR4 rather than CXCR7

Abstract excerpt

BACKGROUND: Maternal-fetal crosstalk during embryo implantation is complex and regulated by local signaling molecules. Chemokines and their receptors are critical signaling components required for implantation and the process of pregnancy. This study aimed to explore whether human first-trimester trophoblast cells (TCs) were capable of modulating the migration and invasion of human first-trimester decidual...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chemokine receptors and signaling
• Share to Preterm Birth and Chorioamnionitis
• Share to Reproductive System and Pregnancy