CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris.

doi:10.1016/j.jaad.2018.02.034

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Article

CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris.

Journal of the American Academy of Dermatology - 1 Sept 2018

Craiglow Brittany G, Boyden Lynn M, Hu Ronghua, Virtanen Marie, Su John, Rodriguez Gabriela, McCarthy Catherine, Luna Paula, Larralde Margarita, Humphrey Stephen, Holland Kristen E, Hogeling Marcia, Hidalgo-Matlock Benjamin, Ferrari Bruno, Fernandez-Faith Esteban, Drolet Beth, Cordoro Kelly M, Bowcock Anne M, Antaya Richard J, Ashack Kurt, Ashack Richard J, Lifton Richard P, Milstone Leonard M, Paller Amy S, Choate Keith A

Abstract excerpt

BACKGROUND: Heterozygous mutations in caspase recruitment domain family member 14 gene (CARD14) have been shown to be associated with psoriasis and familial pityriasis rubra pilaris (PRP). Many subjects with CARD14 mutations display features of both disorders, which can result in diagnostic uncertainty. In addition, these eruptions are often recalcitrant to conventional psoriasis therapies such as methotrexate,...

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PMID: 29477734
DOI: 10.1016/j.jaad.2018.02.034
PMCID: PMC6098739

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CARD14

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