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Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis

21 Feb 2018

Abstract excerpt

INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is a debilitating neurologic disorder with poor survival rates and no clear biomarkers for disease diagnosis and prognosis. METHODS: We compared serum microRNA (miRNA) expression from patients with ALS with healthy controls and patients with multiple sclerosis and Alzheimer disease. We also correlated miRNA expression in cross-sectional and longitudinal cohorts of...

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PMID: 29466830
DOI: 10.1002/mus.26106

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